Methylation Support provides a combination of B vitamins, choline, and betaine to help support homocysteine level.¹ Homocysteine is an amino acid that can be further metabolized into methionine or cysteine.¹ Normal homocysteine levels are necessary for the methylation of nucleic acids, proteins and lipids, as well as protein production.¹ A randomized, double-blind trial involving 76 adults demonstrated that supplementation with 1.5 g of betaine daily for six weeks significantly better maintained homocysteine levels when compared to a placebo treatment.² Betaine also helps support liver function through its role in stimulating the production and export of very low density lipoproteins (VLDL) from the liver.³ Methylation Support contains the physiologically active forms of vitamin B₆, folate and vitamin B₁₂, B vitamins involved in tissue formation, red blood cell formation, and macronutrient metabolism, respectively.⁴ As a result of their interrelated pathways, it is important to have metabolic balances between choline, betaine, homocysteine, vitamin B₆, vitamin B₁₂ and folate.