DHA is the primary omega-3 polyunsaturated fatty acid in the brain where it constitutes approximately 30–40% of the phospholipid content in the cerebral cortex and gray matter. DHA helps to support normal neural membrane function, such as neurotransmission, as well as synaptic plasticity, which is a component of memory and learning processes. In a randomized, placebo-controlled clinical trial conducted on 176 healthy young adults, six months of daily supplementation with 1160 mg of DHA significantly improved cognitive function including both working memory and reaction time.